Wurtz-Fittig reaction

The Wurtz-Fittig reaction is the chemical reaction of aryl halides with alkyl halides and sodium metal to give substituted aromatic compounds.[1] [2]

The reaction is named after Charles-Adolphe Wurtz, who discovered in 1855 a similar reaction between two alkyl halides (Wurtz reaction), and Rudolph Fittig, who discovered that also aryl halides undergo this reaction.

References

  1. ^ Bernhard Tollens, Rudolph Fittig (1864). "Ueber die Synthese der Kohlenwasserstoffe der Benzolreihe (p 303)". Annalen der Chemie und Pharmacie 131 (3): 303–323. doi:10.1002/jlac.18641310307. 
  2. ^ Rudolph Fittig, Joseph König (1867). "Ueber das Aethyl- und Diäthylbenzol (p )". Annalen der Chemie und Pharmacie 144 (3): 277–294. doi:10.1002/jlac.18671440308. 

See also